defect, fault, deficiency
Example sentences
車は欠陥がないか最低３ヵ月に１回検査される。
The vehicles are inspected for defects at least every three months.
彼の理論にはまったく欠陥が見当たらない。
I can't find any holes in his theory.
彼の専門的知識の欠陥が昇進を妨げた。
His lack of technical knowledge precluded him from promotion.