to depart, to set out, to start, to be going out
Example sentences
妻は魚のオードブルが好きだからね、釣りに出掛けるときはお許しが出やすいんだよね。
My wife loves fish hors d'oeuvre, so it's easier for me to get a kitchen pass for my fishing.
雨の中を出かけたので、彼は風邪をひいた。
He caught a chill because he went out in the rain.